MCM2 EXPRESSION IN DIFFERENT MOLECULAR SUBTYPES OF EPITHELIAL BREAST CANCERS AND ITS ASSOCIATION WITH CLINICOPATHOLOGICAL PARAMETERS AND KI-67 EXPRESSION

Introduction: Breast cancer is one of the most common malignancies, with few subtypes having a more aggressive outcome and resistance to conventional therapies, Triple Negative Breast Cancers (TNBCs) being one such variant.The Ki-67 lacks reproducibility and a standardised cut-off.MCM2 (Minichromosome Maintenance 2) has role in DNA repair and repli

The accidents Audio of truck crane happen frequently during working because of the structure failure of hoist boom,which result in severe economic loss and casualties.So,the method combining probabilistic and non-probabilistic hybrid reliability theory with Bayesian Network is put forward to analyze the reliability of hoist boom structure.Probabili

Chaos and unpredictability are traditionally synonymous, yet large-scale machine-learning methods recently have demonstrated a Tick Repellents surprising ability to forecast chaotic systems well beyond typical predictability horizons.However, recent works disagree on whether specialized methods grounded in dynamical systems theory, such as reservoi

Abstract Accelerating climate change has harmed food and water security and affected both terrestrial and aquatic systems, hindering efforts to meet many Sustainable Development Goals [SDGs].Climate finance can help mobilize financial resources and tackle the effects of climate change.This study analyzes existing literature on climate finance more

The Notch-Delta signaling pathway mediates cell differentiation implicated in many regulatory processes including spatiotemporal patterning in tissues by promoting alternate cell fates between neighboring cells.At the multicellular level, this "lateral inhibition" principle leads to checkerboard patterns with alternation of Sender and Receiver cell